Fangrui Wu Selected Research

SEC Translocation Channels

1/2022	A proteolysis-targeting chimera molecule selectively degrades ENL and inhibits malignant gene expression and tumor growth.
1/2021	Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Fangrui Wu Research Topics

Disease

10	Neoplasms (Cancer) 07/2022 - 09/2015
4	Leukemia 01/2022 - 03/2016
3	Dengue (Dengue Fever) 12/2021 - 01/2019
2	Breast Neoplasms (Breast Cancer) 01/2020 - 01/2020
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2018 - 01/2017
2	Glioma (Gliomas) 01/2018 - 09/2015
1	Hematologic Neoplasms (Hematological Malignancy) 07/2022
1	Carcinogenesis 01/2022
1	Flavivirus Infections 11/2021
1	Seizures (Absence Seizure) 11/2019
1	Infantile Epileptic-Dyskinetic Encephalopathy 11/2019
1	Brain Diseases (Brain Disorder) 11/2019
1	Zika Virus Infection 01/2019
1	Glioblastoma (Glioblastoma Multiforme) 01/2018

Drug/Important Bio-Agent (IBA)

8	Pharmaceutical PreparationsIBA 07/2022 - 01/2016
6	Biological ProductsIBA 07/2022 - 01/2016
6	Histones (Histone)IBA 07/2022 - 09/2015
4	Lysine (L-Lysine)FDA Link 07/2022 - 01/2016
3	Peptide Hydrolases (Proteases)FDA Link 12/2021 - 01/2019
2	SEC Translocation ChannelsIBA 01/2022 - 01/2021
2	Small Interfering RNA (siRNA)IBA 01/2020 - 01/2020
2	Estrogen ReceptorsIBA 01/2020 - 01/2020
2	Proteins (Proteins, Gene)FDA Link 11/2019 - 01/2017
2	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2018 - 09/2015
1	Proteolysis Targeting ChimeraIBA 01/2022
1	Cyclin TIBA 01/2022
1	Estrogens (Estrogen)FDA Link 01/2020
1	Vigabatrin FDA Link 11/2019
1	Antiviral Agents (Antivirals)IBA 01/2019
1	GlucocorticoidsIBA 01/2018
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2018
1	Betamethasone (Celestone)FDA Link 01/2018
1	Transcription Factors (Transcription Factor)IBA 01/2018
1	MethyltransferasesIBA 03/2016
1	EnzymesIBA 01/2016
1	Oxidoreductases (Dehydrogenase)IBA 09/2015
1	isocitric acid (isocitrate)IBA 09/2015

Therapy/Procedure

3	Therapeutics 01/2018 - 01/2016